QUESTION & ANSWER
Q: Can you take ibuprofen and extra strength Tylenol together?

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A:

It’s generally safe to take ibuprofen (Advil, Motrin) and extra strength Tylenol together. You can alternate ibuprofen and two extra strength Tylenol tablets every three hours. Or you can take them together every six hours. Don’t exceed six extra strength Tylenol tablets in 24 hours.

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  1. Acetaminophen (Oral Route, Rectal Route). Mayo Foundation for Medical Education and Research. https://www.mayoclinic.org/drugs-supplements/acetaminophen-oral-route-rectal-route/proper-use/drg-20068480
  2. Which OTC Painkillers Can You Take Together? American Council on Science and Health. https://www.acsh.org/news/2018/08/28/which-otc-painkillers-can-you-take-together-13353