QUESTION & ANSWER
Q: What is the best H2 blocker?

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A:

There are four drugs in the H2 blocker class—cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), and ranitidine (Zantac). Each works about as well as the other. Choosing one is largely a matter of preference. However, famotidine and nizatidine are least likely to cause problems with drug interactions.

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  1. H2 Blockers. U.S. National Library of Medicine. https://medlineplus.gov/ency/patientinstructions/000382.htm
  2. Histamine H2 Antagonist (Oral Route, Injection Route, Intravenous Route). Mayo Foundation for Medical Education and Research. https://www.mayoclinic.org/drugs-supplements/histamine-h2-antagonist-oral-route-injection-route-intravenous-route/description/drg-20068584