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WELLBUTRIN SR bupropion hydrochloride

Get an overview of WELLBUTRIN SR (bupropion hydrochloride tablet, film coated), including its generic name, formulation (i.e. pill, oral solution, injection, inhaled medicine) and why it’s used. The medication in WELLBUTRIN SR can be sold under different names.

Refer to the “Also Known As” section to reference different products that include the same medication as WELLBUTRIN SR.

Drug Basics

Brand Name: WELLBUTRIN SR

Generic Name: BUPROPION HYDROCHLORIDE

Drug Type: HUMAN PRESCRIPTION DRUG

Route: ORAL

Dosage Form: TABLET, FILM COATED

Packager: GlaxoSmithKline LLC

Data Current As Of: 2021-02-11

Indications & Usage

WELLBUTRIN SR (bupropion hydrochloride) is indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM).

The efficacy of bupropion in the treatment of a major depressive episode was established in two 4-week controlled inpatient trials and one 6-week controlled outpatient trial of adult subjects with MDD [see Clinical Studies (14)].

The efficacy of WELLBUTRIN SR in maintaining an antidepressant response for up to 44 weeks following 8 weeks of acute treatment was demonstrated in a placebo‑controlled trial [see Clinical Studies (14)].

  •  WELLBUTRIN SR is an aminoketone antidepressant, indicated for the treatment of major depressive disorder (MDD). (1)

Patient Counseling Information

Advise the patient to read the FDA-approved patient labeling (Medication Guide).

Suicidal Thoughts and Behaviors

Instruct patients, their families, and/or their caregivers to be alert to the emergence of anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania, mania, other unusual changes in behavior, worsening of depression, and suicidal ideation, especially early during antidepressant treatment and when the dose is adjusted up or down. Advise families and caregivers of patients to observe for the emergence of such symptoms on a day-to-day basis, since changes may be abrupt. Such symptoms should be reported to the patient’s prescriber or healthcare professional, especially if they are severe, abrupt in onset, or were not part of the patient’s presenting symptoms. Symptoms such as these may be associated with an increased risk for suicidal thinking and behavior and indicate a need for very close monitoring and possibly changes in the medication.

Neuropsychiatric Adverse Events and Suicide Risk in Smoking Cessation Treatment

Although WELLBUTRIN SR is not indicated for smoking cessation treatment, it contains the same active ingredient as ZYBAN which is approved for this use. Inform patients that some patients have experienced changes in mood (including depression and mania), psychosis, hallucinations, paranoia, delusions, homicidal ideation, aggression, hostility, agitation, anxiety, and panic, as well as suicidal ideation and suicide when attempting to quit smoking while taking bupropion. Instruct patients to discontinue bupropion and contact a healthcare professional if they experience such symptoms [see Warnings and Precautions (5.2), Adverse Reactions (6.2)].

Severe Allergic Reactions

Educate patients on the symptoms of hypersensitivity and to discontinue WELLBUTRIN SR if they have a severe allergic reaction.

Seizure

Instruct patients to discontinue and not restart WELLBUTRIN SR if they experience a seizure while on treatment. Advise patients that the excessive use or abrupt discontinuation of alcohol, benzodiazepines, antiepileptic drugs, or sedatives/hypnotics can increase the risk of seizure. Advise patients to minimize or avoid use of alcohol.

As the dose is increased during initial titration to doses above 150 mg/day, instruct patients to take WELLBUTRIN SR in 2 divided doses, preferably with at least 8 hours between successive doses, to minimize the risk of seizures.

Angle-Closure Glaucoma

Patients should be advised that taking WELLBUTRIN SR can cause mild pupillary dilation, which in susceptible individuals, can lead to an episode of angle-closure glaucoma. Pre-existing glaucoma is almost always open-angle glaucoma because angle-closure glaucoma, when diagnosed, can be treated definitively with iridectomy. Open-angle glaucoma is not a risk factor for angle-closure glaucoma. Patients may wish to be examined to determine whether they are susceptible to angle closure, and have a prophylactic procedure (e.g., iridectomy), if they are susceptible [see Warnings and Precautions (5.7)].

Bupropion-Containing Products

Educate patients that WELLBUTRIN SR contains the same active ingredient (bupropion hydrochloride) found in ZYBAN, which is used as an aid to smoking cessation treatment, and that WELLBUTRIN SR should not be used in combination with ZYBAN or any other medications that contain bupropion (such as WELLBUTRIN, the immediate-release formulation and WELLBUTRIN XL or FORFIVO XL, the extended-release formulations, and APLENZIN, the extended-release formulation of bupropion hydrobromide). In addition, there are a number of generic bupropion HCl products for the immediate-, sustained-, and extended-release formulations.

Potential for Cognitive and Motor Impairment

Advise patients that any CNS‑active drug like WELLBUTRIN SR may impair their ability to perform tasks requiring judgment or motor and cognitive skills. Advise patients that until they are reasonably certain that WELLBUTRIN SR does not adversely affect their performance, they should refrain from driving an automobile or operating complex, hazardous machinery. WELLBUTRIN SR may lead to decreased alcohol tolerance.

Concomitant Medications

Counsel patients to notify their healthcare provider if they are taking or plan to take any prescription or over‑the‑counter drugs because WELLBUTRIN SR sustained-release tablets and other drugs may affect each others’ metabolisms.

Pregnancy

Advise patients to notify their healthcare provider if they become pregnant or intend to become pregnant during therapy with WELLBUTRIN SR. Advise patients that there is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to WELLBUTRIN SR during pregnancy [see Use in Specific Populations (8.1)].

Storage Information

Instruct patients to store WELLBUTRIN SR at room temperature, between 68°F and 77°F (20°C to 25°C) and keep the tablets dry and out of the light.

Administration Information

Instruct patients to swallow WELLBUTRIN SR tablets whole so that the release rate is not altered. Do not chew, divide, or crush tablets; they are designed to slowly release drug in the body. When patients take more than 150 mg/day, instruct them to take WELLBUTRIN SR in 2 doses at least 8 hours apart, to minimize the risk of seizures. Instruct patients if they miss a dose, not to take an extra tablet to make up for the missed dose and to take the next tablet at the regular time because of the dose-related risk of seizure. Instruct patients that WELLBUTRIN SR tablets may have an odor. WELLBUTRIN SR can be taken with or without food.

WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, and ZYBAN are trademarks owned by or licensed to the GSK group of companies. The other brands listed are trademarks owned by or licensed to their respective owners and are not owned by or licensed to the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products.

GlaxoSmithKline

Research Triangle Park, NC 27709

©2020 GSK group of companies or its licensor.

WLS:19PI

Medication Guide

WELLBUTRIN SR (WELL byu-trin)

(bupropion hydrochloride) Sustained‑Release Tablets

IMPORTANT: Be sure to read the three sections of this Medication Guide. The first section is about the risk of suicidal thoughts and actions with antidepressant medicines; the second section is about the risk of changes in thinking and behavior, depression and suicidal thoughts or actions with medicines used to quit smoking; and the third section is entitled “What Other Important Information Should I Know About WELLBUTRIN SR?”

Antidepressant Medicines, Depression and Other Serious Mental Illnesses, and Suicidal Thoughts or Actions

This section of the Medication Guide is only about the risk of suicidal thoughts and actions with antidepressant medicines.

What is the most important information I should know about antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions?

  • 1. Antidepressant medicines may increase the risk of suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment.
  • 2. Depression or other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions. These include people who have (or have a family history of) bipolar illness (also called manic-depressive illness) or suicidal thoughts or actions.
  • 3. How can I watch for and try to prevent suicidal thoughts and actions in myself or a family member?
    • 1.Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
    • 2.Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
    • 3.Keep all follow-up visits with your healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.

Call your healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you:

  • thoughts about suicide or dying
  • attempts to commit suicide
  • new or worse depression
  • new or worse anxiety
  • feeling very agitated or restless
  • panic attacks
  • trouble sleeping (insomnia)
  • new or worse irritability
  • acting aggressive, being angry, or violent
  • acting on dangerous impulses
  • an extreme increase in activity and talking (mania)
  • other unusual changes in behavior or mood

What else do I need to know about antidepressant medicines?

  • Never stop an antidepressant medicine without first talking to a healthcare provider. Stopping an antidepressant medicine suddenly can cause other symptoms.
  • Antidepressants are medicines used to treat depression and other illnesses. It is important to discuss all the risks of treating depression and also the risks of not treating it. Patients and their families or other caregivers should discuss all treatment choices with the healthcare provider, not just the use of antidepressants.
  • Antidepressant medicines have other side effects. Talk to the healthcare provider about the side effects of the medicine prescribed for you or your family member.
  • Antidepressant medicines can interact with other medicines. Know all of the medicines that you or your family member takes. Keep a list of all medicines to show the healthcare provider. Do not start new medicines without first checking with your healthcare provider.

It is not known if WELLBUTRIN SR is safe and effective in children under the age of 18.

Quitting Smoking, Quit-Smoking Medications, Changes in Thinking and Behavior, Depression, and Suicidal Thoughts or Actions

This section of the Medication Guide is only about the risk of changes in thinking and behavior, depression and suicidal thoughts or actions with drugs used to quit smoking. Although WELLBUTRIN SR is not a treatment for quitting smoking, it contains the same active ingredient (bupropion hydrochloride) as ZYBAN which is used to help patients quit smoking.

Talk to your healthcare provider or your family member’s healthcare provider about:

  • all risks and benefits of quit-smoking medicines
  • all treatment choices for quitting smoking

When you try to quit smoking, with or without bupropion you may have symptoms that may be due to nicotine withdrawal, including:
  • urge to smoke
  • depressed mood
  • trouble sleeping
  • irritability
  • frustration
  • anger
  • feeling anxious
  • difficulty concentrating
  • restlessness
  • decreased heart rate
  • increased appetite
  • weight gain

Some people have even experienced suicidal thoughts when trying to quit smoking without medication. Sometimes quitting smoking can lead to worsening of mental health problems that you already have, such as depression.

Some people have had serious side effect while taking bupropion to help them quit smoking, including:

New or worse mental health problems, such as changes in behavior or thinking, aggression, hostility, agitation, depression, or suicidal thoughts or actions. Some people had these symptoms when they began taking bupropion, and others developed them after several weeks of treatment, or after stopping bupropion. These symptoms happened more often in people who had a history of mental health problems before taking bupropion than in people without a history of mental health problems.

Stop taking WELLBUTRIN SR and call your healthcare provider right away if you, your family, or caregiver notice any of these symptoms. Work with your healthcare provider to decide whether you should continue to take WELLBUTRIN SR. In many people, these symptoms went away after stopping WELLBUTRIN SR, but in some people, symptoms continued after stopping WELLBUTRIN SR. It is important for you to follow-up with your healthcare provider until your symptoms go away. Before taking WELLBUTRIN SR, tell your healthcare provider if you have ever had depression or other mental health problems. You should also tell your healthcare provider about any symptoms you had during other times you tried to quit smoking, with or without bupropion.

What Other Important Information Should I Know About WELLBUTRIN SR?

  • Seizures: There is a chance of having a seizure (convulsion, fit) with WELLBUTRIN SR, especially in people:
    • with certain medical problems.
    • who take certain medicines.
  •  The chance of having seizures increases with higher doses of WELLBUTRIN SR. For more information, see the sections “Who should not take WELLBUTRIN SR?” and “What should I tell my healthcare provider before taking WELLBUTRIN SR?” Tell your healthcare provider about all of your medical conditions and all the medicines you take. Do not take any other medicines while you are taking WELLBUTRIN SR unless your healthcare provider has said it is okay to take them.
  •   If you have a seizure while taking WELLBUTRIN SR, stop taking the tablets and call your healthcare provider right away. Do not take WELLBUTRIN SR again if you have a seizure.
  • High blood pressure (hypertension). Some people get high blood pressure, that can be severe, while taking WELLBUTRIN SR. The chance of high blood pressure may be higher if you also use nicotine replacement therapy (such as a nicotine patch) to help you stop smoking (see the section of this Medication Guide called “How should I take WELLBUTRIN SR?”).
  • Manic episodes. Some people may have periods of mania while taking WELLBUTRIN SR, including:
    • Greatly increased energy
    • Severe trouble sleeping
    • Racing thoughts
    • Reckless behavior
    • Unusually grand ideas
    • Excessive happiness or irritability
    • Talking more or faster than usual

  •  If you have any of the above symptoms of mania, call your healthcare provider.

  • Unusual thoughts or behaviors. Some patients have unusual thoughts or behaviors while taking WELLBUTRIN SR, including delusions (believe you are someone else), hallucinations (seeing or hearing things that are not there), paranoia (feeling that people are against you), or feeling confused. If this happens to you, call your healthcare provider.
  • Visual problems.
    • eye pain
    • changes in vision
    • swelling or redness in or around the eye
  •  Only some people are at risk for these problems. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are.
  • Severe allergic reactions. Some people can have severe allergic reactions to WELLBUTRIN SR. Stop taking WELLBUTRIN SR and call your healthcare provider right away if you get a rash, itching, hives, fever, swollen lymph glands, painful sores in the mouth or around the eyes, swelling of the lips or tongue, chest pain, or have trouble breathing. These could be signs of a serious allergic reaction.

What is WELLBUTRIN SR?

WELLBUTRIN SR is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder.

Who should not take WELLBUTRIN SR?

Do not take WELLBUTRIN SR if you

  • have or had a seizure disorder or epilepsy.
  • have or had an eating disorder such as anorexia nervosa or bulimia.
  • are taking any other medicines that contain bupropion, including ZYBAN (used to help people stop smoking), WELLBUTRIN, WELLBUTRIN XL, APLENZIN, or FORFIVO XL. Bupropion is the same active ingredient that is in WELLBUTRIN SR.
  • drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti-seizure medicines, and you stop using them all of a sudden.
  • take a monoamine oxidase inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid.
    • do not take an MAOI within 2 weeks of stopping WELLBUTRIN SR unless directed to do so by your healthcare provider.
    • do not start WELLBUTRIN SR if you stopped taking an MAOI in the last 2 weeks unless directed to do so by your healthcare provider.
  • are allergic to the active ingredient in WELLBUTRIN SR, bupropion, or to any of the inactive ingredients. See the end of this Medication Guide for a complete list of ingredients in WELLBUTRIN SR.

What should I tell my healthcare provider before taking WELLBUTRIN SR?

Tell your healthcare provider if you have ever had depression, suicidal thoughts or actions, or other mental health problems. See “Antidepressant Medicines, Depression and Other Serious Mental Illnesses, and Suicidal Thoughts or Actions.”

  • Tell your healthcare provider about your other medical conditions including if you:
    • have liver problems, especially cirrhosis of the liver.
    • have kidney problems.
    • have, or have had, an eating disorder, such as anorexia nervosa or bulimia.
    • have had a head injury.
    • have had a seizure (convulsion, fit).
    • have a tumor in your nervous system (brain or spine).
    • have had a heart attack, heart problems, or high blood pressure.
    • are a diabetic taking insulin or other medicines to control your blood sugar.
    • drink alcohol.
    • abuse prescription medicines or street drugs.
    • are pregnant or plan to become pregnant. Talk to your healthcare provider about the risk to your unborn baby if you take WELLBUTRIN SR during pregnancy.
      • Tell your healthcare provider if you become pregnant or think you are pregnant during treatment with WELLBUTRIN SR.
      • If you become pregnant during treatment with WELLBUTRIN SR, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants. You can register by calling 1-844-405-6185.
    • are breastfeeding or plan to breastfeed during treatment with WELLBUTRIN SR. WELLBUTRIN SR passes into your milk. Talk to your healthcare provider about the best way to feed your baby during treatment with WELLBUTRIN SR.

Tell your healthcare provider about all the medicines you take, including prescription, over-the-counter medicines, vitamins, and herbal supplements. Many medicines increase your chances of having seizures or other serious side effects if you take them while you are taking WELLBUTRIN SR.

How should I take WELLBUTRIN SR?

  • Take WELLBUTRIN SR exactly as prescribed by your healthcare provider. Do not change your dose or stop taking WELLBUTRIN SR without talking to your healthcare provider first.
  • Swallow WELLBUTRIN SR tablets whole. Do not chew, cut, or crush WELLBUTRIN SR tablets. If you do, the medicine will be released into your body too quickly. If this happens you may be more likely to get side effects including seizures. Tell your healthcare provider if you cannot swallow tablets.
  • WELLBUTRIN SR tablets may have an odor. This is normal.
  • Take WELLBUTRIN SR at the same time each day.
  • Take your doses of WELLBUTRIN SR at least 8 hours apart.
  • You may take WELLBUTRIN SR with or without food.
  • If you miss a dose, do not take an extra dose to make up for the dose you missed. Wait and take your next dose at the regular time. This is very important. Too much WELLBUTRIN SR can increase your chance of having a seizure.
  • If you take too much WELLBUTRIN SR, or overdose, call your local emergency room or poison control center right away.
  • Do not take any other medicines while taking WELLBUTRIN SR unless your healthcare provider has told you it is okay.
  • If you are taking WELLBUTRIN SR for the treatment of major depressive disorder, it may take several weeks for you to feel that WELLBUTRIN SR is working. Once you feel better, it is important to keep taking WELLBUTRIN SR exactly as directed by your healthcare provider. Call your healthcare provider if you do not feel WELLBUTRIN SR is working for you.

What should I avoid while taking WELLBUTRIN SR?

  • Limit or avoid using alcohol during treatment with WELLBUTRIN SR. If you usually drink a lot of alcohol, talk with your healthcare provider before suddenly stopping. If you suddenly stop drinking alcohol, you may increase your chance of having seizures.
  • Do not drive a car or use heavy machinery until you know how WELLBUTRIN SR affects you. WELLBUTRIN SR can affect your ability to do these things safely.

What are possible side effects of WELLBUTRIN SR?

WELLBUTRIN SR can cause serious side effects. See the sections at the beginning of this Medication Guide for information about serious side effects of WELLBUTRIN.

The most common side effects of WELLBUTRIN SR include:
  • headache
  • dry mouth
  • nausea
  • trouble sleeping
  • dizziness
  • sore throat
  • constipation

If you have nausea, take your medicine with food. If you have trouble sleeping, do not take your medicine too close to bedtime.

Tell your healthcare provider right away about any side effects that bother you.

These are not all the possible side effects of WELLBUTRIN SR. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1‑800-FDA-1088.

You may also report side effects to GlaxoSmithKline at 1-888-825-5249.

How should I store WELLBUTRIN SR?

  • Store WELLBUTRIN SR at room temperature between 68°F and 77°F (20°C to 25°C).
  • Keep WELLBUTRIN SR dry and out of the light.

Keep WELLBUTRIN SR and all medicines out of the reach of children.

General information about the safe and effective use of WELLBUTRIN SR.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use WELLBUTRIN SR for a condition for which it was not prescribed. Do not give WELLBUTRIN SR to other people, even if they have the same symptoms you have. It may harm them.

If you take a urine drug screening test, WELLBUTRIN SR may make the test result positive for amphetamines. If you tell the person giving you the drug screening test that you are taking WELLBUTRIN SR, they can do a more specific drug screening test that should not have this problem.

This Medication Guide summarizes important information about WELLBUTRIN SR. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about WELLBUTRIN SR that is written for healthcare professionals.

For more information about WELLBUTRIN SR, call 1-888-825-5249.

What are the ingredients in WELLBUTRIN SR?

Active ingredient: bupropion hydrochloride.

Inactive ingredients: carnauba wax, cysteine hydrochloride, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, and titanium dioxide. The tablets are printed with edible black ink. In addition, the 100‑mg tablet contains FD&C Blue No. 1 Lake, the 150‑mg tablet contains FD&C Blue No. 2 Lake and FD&C Red No. 40 Lake, and the 200‑mg tablet contains FD&C Red No. 40 Lake. The tablets are printed with edible black ink.

GlaxoSmithKline

Research Triangle Park, NC 27709

WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, and ZYBAN are trademarks owned by or licensed to the GSK group of companies. The other brands listed are trademarks owned or licensed to their respective owners and are not owned by or licensed to the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products.

©2019 GSK group of companies or its licensor.

WLS:15MG

This Medication Guide has been approved by the U.S. Food and Drug Administration.                         Revised: 11/2019

PRINCIPAL DISPLAY PANEL

NDC 0173-0947-55

Wellbutrin SR

(bupropion HCl)

Sustained-Release Tablets

Rx only

Twice-A-Day

(After Initial Titration)

100 mg

Each sustained-release tablet contains 100 mg bupropion HCl.

WARNING: Do not use with other medicines that contain bupropion HCl.

Federal Law requires dispensing of Wellbutrin SR with the Medication Guide provided with this bottle.

See prescribing information for dosage information.

Store at controlled room temperature, 68o to 77oF (20o to 25oC) [see USP].

Keep dry and out of light.

60 Tablets

GlaxoSmithKline

RTP, NC 27709

Made in Spain

Trademark owned or licensed by GSK.

©2019 GSK or licensor.

  •  62000000041493 Rev. 7/19
wellbutrinsr spl graphic 02.jpg

PRINCIPAL DISPLAY PANEL

NDC 0173-0135-55

Wellbutrin SR

(bupropion HCl)

Sustained-Release Tablets

Rx only

Twice-A-Day

(After Initial Titration)

150 mg

Each sustained-release tablet contains 150 mg bupropion HCl.

WARNING: Do not use with other medicines that contain bupropion HCl.

Federal Law requires dispensing of Wellbutrin SR with the Medication Guide provided with this bottle.

See prescribing information for dosage information.

Store at controlled room temperature, 68o to 77oF (20o to 25oC) [see USP].

Keep dry and out of light.

60 Tablets

GlaxoSmithKline

RTP, NC 27709

Made in Spain

Trademark owned or licensed by GSK.

©2019 GSK or licensor.

  •  62000000041495 Rev. 7/19
wellbutrinsr spl graphic 03.jpg

PRINCIPAL DISPLAY PANEL

NDC 0173-0722-00

WellbutrinSR

(bupropion HCl)

Sustained-Release Tablets

Rx only

Twice-A-Day

(After Initial Titration)

200 mg

Each sustained-release tablet contains 200 mg bupropion HCl.

WARNING: Do not use with other medicines that contain bupropion HCl.

Federal Law requires dispensing of Wellbutrin SR with the Medication Guide provided with this bottle.

See prescribing information for dosage information.

Store at controlled room temperature, 68o to 77oF (20o to 25oC) [see USP].

Keep dry and out of light.

60 Tablets

GlaxoSmithKline

RTP, NC 27709

Made in Spain

Trademark owned or licensed by GSK.

©2019 GSK or licensor.

  •  62000000041494 Rev. 7/19
wellbutrinsr spl graphic 04.jpg

also known as
This drug label information is as submitted to the Food and Drug Administration (FDA) and is intended for informational purposes only. If you think you may have a medical emergency, immediately call your doctor or dial 911. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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